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Shih-Kai Wang Assistant Professor

Tel:886-2-23123456 ext 70251
Email:shihkaiw@ntu.edu.tw


Experiences

PhD, University of Michigan, 2014
DDS, National Taiwan University, 2004

Professional specialties

Pediatric Dentistry, Human Genetics, Developmental Biology

Main Research Interests

Mutational analysis of inherited craniofacial and orodental anomalies
Molecular mechanism and genetic regulation of early tooth development
Genetics of dental enamel formation and amelogenesis imperfecta

Selected Publications

  1. Wang SK, Hu Y, Yang J, Smith CE, Richardson AS, Yamakoshi Y, Lee YL, Seymen F, Koruyucu M, Gencay K, Lee M, Choi M, Kim JW, Hu JC, Simmer JP. Fam83h null mice support a neomorphic mechanism for human ADHCAI. Mol Genet Genomic Med. 2016; 4(1):46-67.
  2. Wang SK, Hu Y, Yang J, Smith CE, Nunez SM, Richardson AS, Pal S, Samann AC, Hu JC, Simmer JP. Critical roles for WDR72 in calcium transport and matrix protein removal during enamel maturation. Mol Genet Genomic Med. 2015; 3(4):302-19.
  3. Yang J, Wang SK, Choi M, Reid BM, Hu Y, Lee YL, Herzog CR, Kim-Berman H, Lee M, Benke PJ, Lloyd KC, Simmer JP, Hu JC. Taurodontism, variations in tooth number, and misshapened crowns in Wnt10a null mice and human kindreds. Mol Genet Genomic Med. 2015; 3(1):40-58. (co-first author)
  4. Wang SK, Choi M, Richardson AS, Reid BM, Seymen F, Yildirim M, Tuna EB, Gencay K, Simmer JP, Hu JC. STIM1 and SLC24A4 are critical for enamel maturation. J Dent Res. 2014; 93(7 suppl):94S-100S.
  5. Wang SK, Choi M, Richardson AS, Reid BM, Lin BP, Wang SJ, Kim JW, Simmer JP, Hu JC. ITGB6 loss-of-function mutations cause autosomal recessive amelogenesis imperfecta. Hum Mol Genet. 2014; 23(8):2157-63.
  6. Wang SK, Reid BM, Dugan SL, Roggenbuck JA, Read L, Aref P, Taheri AP, Yeganeh MZ, Simmer JP, Hu JC. FAM20A mutations associated with enamel renal syndrome. J Dent Res. 2014; 93(1):42-8.
  7. Wang SK, Samann AC, Hu JC, Simmer JP. FAM20C functions intracellularly within both ameloblasts and odontoblasts in vivo. J Bone Miner Res. 2013; 28(12):2508-11.
  8. Wang SK, Aref P, Hu Y, Milkovich RN, Simmer JP, El-Khateeb M, Daggag H, Baqain ZH, Hu JC. FAM20A mutations can cause enamel-renal syndrome (ERS). PLoS Genet. 2013; 9(2):e1003302.
  9. Wang SK, Hu Y, Simmer JP, Seymen F, Estrella NM, Pal S, Reid BM, Yildirim M, Bayram M, Bartlett JD, Hu JC. Novel KLK4 and MMP20 mutations discovered by whole-exome sequencing. J Dent Res. 2013; 92(3):266-71.
  10. Wang SK, Chan HC, Makovey I, Simmer JP, Hu JC. Novel PAX9 and COL1A2 missense mutations causing tooth agenesis and OI/DGI without skeletal abnormalities. PLoS One. 2012; 7(12):e51533.

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